Prediction of metabolic and cardiopulmonary responses to maximum cycle ergometry: a randomised study.

نویسندگان

  • J A Neder
  • L E Nery
  • A Castelo
  • S Andreoni
  • M C Lerario
  • A Sachs
  • A C Silva
  • B J Whipp
چکیده

All of the most widely-cited studies for the prediction of maximum exercise responses have utilized either volunteers or referred subjects. Therefore, selection bias, with overestimation of the reference values, is a likely consequence. In order to establish a set of predictive equations for the gas exchange, ventilatory and cardiovascular responses to maximum ramp-incremental cycle ergometry, this study prospectively evaluated 120 sedentary individuals (60 males, 60 females, aged 20-80), randomly-selected from >8,000 subjects. Regular physical activity pattern by questionnaire, body composition by anthropometry and dual energy X-ray absorptiometry (n = 75) and knee strength by isokinetic dynamometry were also assessed. Previously reported equations typically overestimated the subjects' peak oxygen uptake (p<0.05). Prediction linear equations for the main variables of clinical interest were established by backward stepwise regression analysis including: sex, age, knee extensor peak torque, bone-free lean leg mass, total and lean body mass, height, and physical activity scores. Reference intervals (95% confidence limits) were calculated: some of these values differed markedly from those formerly recommended. The results therefore might provide a more appropriate frame of reference for interpretation of the responses to symptom-limited ramp incremental cycle ergometry in sedentary subjects; i.e. those usually referred for clinical cardiopulmonary exercise tests.

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REFERENCES 1 ERS Task Force, Palange P, Ward SA, et al. Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007; 29: 185– 209. 2 Koch B, Schäper C, Ittermann T, et al. Reference values for cardiopulmonary exercise testing in healthy volunteers: the SHIP study. Eur Respir J 2009; 33: 389–397. 3 Stewart KJ. Physical activity and aging. Ann N Y Acad Sci 2005; 1055: 1...

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REFERENCES 1 Koch B, Schäper C, Ittermann T, et al. Reference values for cardiopulmonary exercise testing in healthy volunteers: the SHIP study. Eur Respir J 2009; 33: 389–397. 2 John U, Greiner B, Hensel E, et al. Study of Health In Pomerania (SHIP): a health examination survey in an east German region: objectives and design. Soz Praventivmed 2001; 46: 186–194. 3 Neder JA, Nery LE, Castelo A, ...

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عنوان ژورنال:
  • The European respiratory journal

دوره 14 6  شماره 

صفحات  -

تاریخ انتشار 1999